Caffeine in coffee reduces the severity of liver
fibrosis in patients with chronic hepatitis C virus, a new study has found.
Liver fibrosis (scarring of the liver) is the second stage of liver
disease during which liver function declines because of accumulated connective
tissue.
The new U.S. National Institutes of Health study included 177
patients, mean age 51, whose daily consumption of caffeine from food and
beverages was tracked for two years.
Patients who consumed more than 308
milligrams of caffeine from coffee per day had milder liver fibrosis than other
patients. The daily amount of caffeine intake found to be beneficial is
equivalent to 2.25 cups of regular coffee. For each 67-milligram increase in
caffeine consumption (about one half cup of coffee), there was a 14 percent
decrease in the odds of advanced fibrosis for patients with hepatitis C virus.
Other sources of caffeine -- such as soft drinks, tea,
caffeine-fortified drinks and caffeine pills -- didn't have the same helpful
effect, according to the study published in the January issue of the journal
Hepatology.
The researchers said further research is needed to determine
whether the protective effects of coffee/caffeine increase at levels beyond
normal daily intake.
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